Pubdate: Thu, 20 Aug 1998 Date: 08/20/1998 Source: New York Times (NY) Author: Eric J. Simon Website: http://www.nytimes.com/ To the Editor: Re "Giuliani Orders 5 City Hospitals to Wean Addicts Off Methadone" (front page, Aug. 15): I do not know where Mayor Rudolph W. Giuliani's experts get their information, but there is abundant evidence showing that the majority of addicts withdrawn from methadone revert to street use of intravenous heroin. The Mayor is wrong in arguing that methadone substitutes one dependency for another. Patients do not get a "high" from methadone. They quickly develop tolerance to the oral drug. The analogy to insulin is a far more apt one. Mayor Giuliani is in the process of destroying the only drug abuse treatment program widely acknowledged by medical and drug abuse experts to work. Eric J. Simon New York The writer is a professor of psychiatry and pharmacology at New York University Medical Center.